Best answer: Is Zejula a chemo drug?

Is ZEJULA chemotherapy?

FDA approval

Zejula was the first PARP drug approved for ovarian cancer that has responded to chemotherapy that’s made with platinum. Then, in 2020, the FDA expanded Zejula’s approval to include treatment of advanced ovarian cancer that’s already been treated with three or more chemotherapy regimens.

What type of drug is ZEJULA?


Zejula (niraparib) is an oral, once-daily poly(ADP-ribose) polymerase inhibitor (PARP inhibitor). PARP, or poly(ADP-ribose) polymerase, is a protein that helps repair damaged DNA. PARP inhibitors are targeted therapies that are used in the treatment of certain cancers.

Is ZEJULA an immunotherapy?

Zejula + Keytruda. The cancer immunotherapy strategy known as programmed cell death 1 (PD-1) has generated great excitement for its ability to help the immune system recognize, and attack cancer.

Are PARP inhibitors considered chemotherapy?

PARP inhibitors interfere with certain enzymes that help cancer cells repair. Blocking these enzymes allows the cancer cells to die. These inhibitors are targeted therapies — they target cancer cells and have less effect on healthy cells than traditional chemotherapy.

When do you start ZEJULA?

For the maintenance treatment of advanced ovarian cancer, patients should start treatment with ZEJULA no later than 12 weeks after their most recent platinum-containing regimen. Maintenance Treatment of Recurrent Ovarian Cancer The recommended dose of ZEJULA is 300 mg (three 100-mg capsules) taken orally once daily.

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Does ZEJULA cause joint pain?

altered sense of taste; back pain, muscle or joint pain; headache, dizziness, anxiety; sleep problems (insomnia);

Can ZEJULA cause high blood pressure?

This medication may raise your blood pressure and heart rate. Sometimes these effects can be serious. Check your blood pressure and heart rate regularly and tell your doctor if the results are high. Your doctor may control your blood pressure and heart rate with medication.

Do ZEJULA side effects go away?

Some side effects of niraparib may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Does ZEJULA prolong life?

In a new study, Zejula (niraparib) has been shown to prolong life for patients with ovarian cancer who have already undergone four or more rounds of chemotherapy. Ovarian cancer is the deadliest gynecologic cancer in the US, with 70% of patients relapsing after first responding to initial treatment.

Is ZEJULA safe to take?

Serious Side Effects

Symptoms of low blood cell counts (low red blood cells, low white blood cells, and low platelets) are common during treatment with ZEJULA. They can be a sign of serious bone marrow problems, including MDS or AML. These symptoms may include the following: Weakness.

Is ZEJULA better than Lynparza?

GlaxoSmithKline’s Zejula jumps ahead of Lynparza with all-comers ovarian cancer nod. Since late 2018, women with ovarian cancer who responded to an initial round of chemo have been eligible to receive a PARP inhibitor, but only if they had a BRCA mutation. Now, GlaxoSmithKline’s Zejula has changed that.

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Does Niraparib cause insomnia?

Unfortunately, the patient developed side effects to niraparib, including insomnia, thrombocytopenia, and neutropenia.

How long do you take PARP inhibitors?

We often have long discussions among ourselves and with the patients about how long to continue PARP inhibitors. Some studies continue them for up to 2 years. Niraparib has been continued for up to 3 years.

Can I take Gaviscon while on chemotherapy?

Antacids. Antacids function by neutralizing stomach acid. Despite the relative safety of their ingredients, antacids should not be taken in excess of the dosing recommendations on the label or with certain types of chemotherapy due to possible neutralizing effects on chemotherapy and other drug interactions.