Can rituximab cause skin cancer?


Can Rituxan cause skin problems?

There is a chance that you will experience an allergic reaction to Rituximab. Allergic reactions may be mild, such as skin rash or hives or severe, such as breathing difficulties or shock. A severe allergic reaction would require immediate medical treatment and could result in permanent disability or death.

Does rituximab increase risk of cancer?

No evidence of increased risk of malignancy, of any organ-specific type, was found following rituximab treatment. The rate of malignancies from rituximab-treated patients in RA clinical trials was 7.4 per 1000 patient-years.

What are the long term side effects of rituximab?

These adverse events include the development of late-onset neutropenia, defects of immune reconstitution with associated immune compromise, infections, progressive multifocal leukoencephalopathy, reactivation of hepatitis, intestinal perforation and interstitial pneumonitis.

Can Rituxan cause secondary cancer?

Conclusion: Association between rituximab and subsequent development of second malignancies might be a coincidence. However, we suggest close monitoring for second malignancies, particularly skin tumors, in patients treated with rituximab. This issue should be evaluated in further studies.

Does Rituxan lower your immune system?

Rituximab suppresses the immune system. Therefore, serious fungal, bacterial, and new or reactivated viral infections (for example, hepatitis B or C, shingles) can occur during or after treatment with rituximab.

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What does rituximab do to your body?

Rituximab is used to treat certain types of cancer (such as non-Hodgkin’s lymphoma, chronic lymphocytic leukemia). It works by slowing or stopping the growth of cancer cells. Some brands of rituximab are also used to treat rheumatoid arthritis and can decrease joint pain and swelling.

Can rituximab cause breast cancer?

Rituximab does not increase the risk of malignancy or breast cancer….

How long can you stay on rituximab?

This can be anything from six months to a few years later. Many people need to have rituximab infusions at least once a year because of how long the treatment lasts. If you have vasculitis your treatment may be more frequent than this.

What is the success rate of rituximab?

Rituximab was given as a monotherapy on the same dosage schedule as the 1997 study and again achieved a 48% response rate (6% achieved CR) with a median time to progression of approximately 12 months among responders (9).

Does rituximab make you gain weight?

Weight gain or weight loss

Some people took Rituxan afterward and some people didn’t take any medication. Of the people who took Rituxan after chemotherapy, 11% gained weight. In comparison, 4% of people who didn’t take medication after chemotherapy gained weight.