Question: What is the most important prognostic factor in melanoma?

What is the most important prognostic indicator of malignancy?

The most important prognostic factor in all human cancers is the stage at presentation, which is the anatomic extent of the disease.

Which of the two factors is most important when considering the significance of a given melanoma?

Tumor thickness as defined by the Breslow’s Depth of Invasion is the most important determinant of prognosis for melanomas. Increased tumor thickness is correlated with metastasis and poorer prognosis.

Which of the following factors is of most prognostic value in determining survival rates in patients with cutaneous malignant melanoma?

MALIGNANT melanoma exhibits a capricious clinical behavior. Thus, while tumor thickness is the most important prognostic factor determining survival, many patients with thick melanomas are free of metastasis while a small subset of patients with thin tumors die of their disease.

What is the most important prognostic feature of acral melanoma?

Breslow thickness is a continuous variable and is the most important prognostic factor in cutaneous melanoma. Tumor thickness as measured by the Breslow technique was divided into the following 4 categories: 0.01 to 1.00 mm, 1.01 to 2.00 mm, 2.01 to 4.00 mm, and thicker than 4.00 mm.

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What is a poor prognostic indicator?

Answer. Poor prognostic factors include the stage of disease at presentation, which is influenced by presence of nodal and/or distant disease. In particular, the presence of nodal disease influences survival and the likelihood of metastatic disease.

What is a positive prognostic indicator?

Positive Prognostic Indicators. 1. Demonstrates adequate physical, auditory and visual attention to structured speech tasks. 2. Has average or above average intelligence.

Where does melanoma usually spread to first?

Normally, the first place a melanoma tumor metastasizes to is the lymph nodes, by literally draining melanoma cells into the lymphatic fluid, which carries the melanoma cells through the lymphatic channels to the nearest lymph node basin.

How does melanoma make you feel?

Hard lumps may appear in your skin. You may lose your breath, have chest pain or noisy breathing or have a cough that won’t go away. You may feel pain in your liver (the right side of your stomach) Your bones may feel achy.

Can you have melanoma for years and not know?

How long can you have melanoma and not know it? It depends on the type of melanoma. For example, nodular melanoma grows rapidly over a matter of weeks, while a radial melanoma can slowly spread over the span of a decade. Like a cavity, a melanoma may grow for years before producing any significant symptoms.

Which of the following is a potential indicator of malignant melanoma?

The most important prognostic factors include the following : Thickness and/or level of invasion. Mitotic index (mitoses per millimeter) Ulceration or bleeding at the primary site.

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What is the best indicator of prognosis for a melanoma Mcq?

What is the best indicator of prognosis for a melanoma? Question 4 Explanation: Invasion/ depth of extension measured by Breslow thickness is the most significant prognostic factor in predicting metastasis.