Frequent question: Can CA 125 detect stomach cancer?

What cancers does CA 125 detect?

Cancer antigen 125 (CA125) is a protein found on most ovarian cancer cells that is secreted into the blood stream and can be measured.

The CA125 blood levels can be increased in ovarian cancer and other cancers including:

  • uterine.
  • fallopian tube.
  • pancreatic.
  • breast.
  • colorectal.
  • lung.
  • stomach.

Is there a marker for stomach cancer?

In gastric cancer, the most used tumor markers are: CA 72-4, carcinoembryonic antigen (CEA) and cancer-related antigen 19-9 (CA 19-9).

What cancers have elevated CA 125?

Conditions that may cause an elevated CA-125 level in the blood include:

  • Ovarian cancer.
  • Cancers of the pancreas, breast, and lung.
  • Endometriosis.
  • Uterine fibroids.
  • Pregnancy.
  • Menstruation.
  • Liver disease.

What cancer marker is CA 125?

Cancer antigen 125 (CA 125) is the only tumor marker recommended for clinical use in the diagnosis and management of ovarian cancer. The reference range of CA 125 is 0-35 units/mL (0-35 kU/L).

What is a bad CA 125 level?

The tumor marker Ca 125 is a prognostic factor. Levels around 100 U/l are indicative of a bad prognosis.

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What happens if CA 125 is high?

If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer. Your doctor may recommend other tests and procedures to determine your diagnosis.

Does a CEA blood test detect stomach cancer?

High CEA levels may also be a sign of some noncancerous conditions, such as cirrhosis, noncancerous breast disease, and emphysema. A CEA test can’t tell you what kind of cancer you have, or even whether you have cancer. So the test is not used for cancer screening or diagnosis.

What is a high CEA level for stomach cancer?

In patients with nonresectable cancers, the CEA value was 83.0 ± 235.5 ng/ml, the CEA positivity rate was 47.8%. Overall, of 252 patients with primary gastric cancer, 47(18.7%) were positive for CEA. In patients with cancer recurrence, the CEA value averaged 41.8 ± 101.8 ng/ml, the positivity rate was 63%.

Can stress cause CA125 to rise?

The most popular current theories suggest that CA 125 is synthesized by mesothelial cells in response to stress, which can be either mechanical stress caused by fluid overload, or inflammatory stress instigated by the release of mediators such as TNFα and interleukins [5,6].

How can I lower my CA125 naturally?

Exercise and Diet

Foods like beans, eggs, nuts, and other foods that provide Vitamin D are recommended as well as foods high in Vitamin A like carrots, leafy greens, and sweet potatoes.

How accurate is the CA 125 blood test?

Results: Using a CA125 cutoff of 30 U/mL, an overall sensitivity of 94.8% (96.6% specificity) was obtained when comparing malignancies versus healthy postmenopausal controls, whereas a cutoff of 65 U/mL provided a sensitivity of 83.9% (99.6% specificity).

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Can you be fully cured of ovarian cancer?

Approximately 20% of women with advanced-stage ovarian cancer survive beyond 12 years after treatment and are effectively cured. Initial therapy for ovarian cancer comprises surgery and chemotherapy, and is given with the goal of eradicating as many cancer cells as possible.

Does high CA125 always mean cancer?

Does a high CA-125 always mean cancer? No, a high CA-125 does not always mean cancer is present. Generally speaking, the normal range of CA-125 is considered to be 0-35 units/mL, while a level above 35 units/mL is considered to be a high CA-125 level.

How high can CA125 levels go?

High levels of CA 125 (from 125 to 10.000 U/ml and higher) were revealed in 54 from 57 patients (94.7%) with malignant ovarian tumors.