How do you treat Angioimmunoblastic lymphoma?


Can Angioimmunoblastic cell lymphoma be cured?

In general, relapsed lymphoma remains potentially curable; however, required approaches are significantly more aggressive and therefore riskier than the initial treatment. AITL cure remains elusive in the majority of patients.

What is the survival rate for AITL?

AITL can occasionally spontaneously remit, though almost never does so permanently. The complete remission rate with CHOP is 64% with a median survival of 19 months. The 5 year overall survival is 32% with a 5 year failure free survival of 18%. Survival is dependent on the International Prognostic Index (IPI) score.

What is the cause of Angioimmunoblastic T-cell lymphoma?

Suspected risk factors include several viruses including the Epstein-Barr virus, cytomegalovirus, hepatitis C virus, human herpes viruses 6 and 8, and the human immunodeficiency virus. Certain infectious agents including tuberculosis and Cryptococcus have also been linked to AITL.

What are the symptoms of Angioimmunoblastic T-cell lymphoma?

The most common symptoms of AITL and FTCL are:

  • fever, night sweats and unexplained weight loss (‘B symptoms’)
  • swollen lymph nodes, usually in several places.
  • a swollen liver and spleen, which might make you feel bloated or cause tummy (abdominal) pain.
  • itching.
  • skin rash.
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Is T-cell lymphoma a rare disease?

Angioimmunoblastic T-Cell Lymphoma (AITL) is a rare, aggressive type accounting for about seven percent of all patients with T-cell lymphomas in the United States. Most patients are middle-aged to elderly and are diagnosed with advanced stage disease.

What does Angioimmunoblastic T-cell lymphoma mean?

Listen to pronunciation. (AN-jee-oh-IH-myoo-noh-BLAS-tik T-sel lim-FOH-muh) An aggressive (fast-growing) type of T-cell non-Hodgkin lymphoma marked by enlarged lymph nodes and hypergammaglobulinemia (increased antibodies in the blood).

What is Angioimmunoblastic lymphoma?

AITL is a type of peripheral T-cell lymphoma. It is a high grade (aggressive) lymphoma that affects blood cells called T cells. High grade lymphomas tend to grow more quickly than low grade lymphomas. AITL usually affects older people, typically around the age of 70.

Is lymphoma an infection?

Infections. Lymphoma is not infectious. You cannot catch lymphoma and you cannot pass it on to someone else.

Can AITL be cured?

There has been no survival improvement for AITL patients over the past two decades. Further investigations are warranted to develop more effective treatment for AITL.

What does Chop mean chemo?

(… REH-jih-men) An abbreviation for a chemotherapy combination that is used to treat non-Hodgkin lymphoma and is being studied in the treatment of other types of cancer. It includes the drugs cyclophosphamide, doxorubicin hydrochloride (hydroxydaunorubicin), vincristine sulfate (Oncovin), and prednisone.

Is mycosis fungoides caused by a fungal infection?

Mycosis fungoides was first described in 1806 by French dermatologist Jean-Louis-Marc Alibert. The name mycosis fungoides is very misleading—it loosely means “mushroom-like fungal disease”. The disease, however, is not a fungal infection but rather a type of non-Hodgkin’s lymphoma.

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Is T-cell lymphoma the same as non Hodgkin’s?

T-cell lymphomas are non-Hodgkin lymphomas that develop from T lymphocytes. Some T-cell lymphomas develop in the skin.

Is T-cell lymphoma hereditary?

Genetics: Genetic factors might be involved in the development of some types of T-cell skin lymphoma. Mycosis fungoides, the most common type, can occasionally run in families but this is very rare.

Is stage 4 non Hodgkin’s lymphoma survival rate?

For stage IV NHL, the 5-year survival rate is around 63%. These survival rates vary depending on the cancer’s stage and subtype. It is important to remember that statistics on the survival rates for people with NHL are an estimate.