Quick Answer: Is germ cell tumors aggressive?

Can germ cell tumors spread?

Germ cell tumors can spread (metastasize) to other parts of the body. The most common sites for metastasis are the lungs, liver, lymph nodes, and central nervous system. Rarely, germ cell tumors can spread to the bone, bone marrow, and other organs.

Is a germ cell tumor that grows quickly?

There are 2 different categories of germ cell tumors that start in the testicles or ovaries: seminomas and non-seminomas. Generally, non-seminomas tend to grow and spread more quickly than seminomas, but prompt diagnosis and treatment are important for both types of germ cell tumors.

What is the survival rate of germ cell tumor?

The 5-year survival rate for teens ages 15 to 19 is 93%. The survival and cure rates also depend on several factors, including the stage of the disease. The cure rate for children with a stage I or stage II germ cell tumor is 90%. The cure rate for a stage III tumor is 87%.

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Who gets germ cell tumors?

Ovarian germ cell tumors usually occur in teenage girls or young women and most often affect just one ovary. The ovaries are a pair of organs in the female reproductive system. They are in the pelvis, one on each side of the uterus (the hollow, pear-shaped organ where a fetus grows).

Is germ cell tumor curable?

Most ovarian germ cell tumors are treatable. For malignant tumors, the prognosis depends on the tumor’s size and if cancer has spread to other parts of the body.

What percentage of germ cell tumors are malignant?

Malignant germ cell tumors of the mediastinum are uncommon, representing only 3 to 10% of tumors originating in the mediastinum. They are much less common than germinal tumors arising in the testes, and account for only 1 to 5% of all germ cell neoplasms.

What causes germ cell Tumours?

The cause of most germ cell tumors isn’t always known. Doctors do know that some medical conditions can make children more likely to develop them. These include: birth defects that involve the central nervous system, genitals, urinary tract, and spine.

How do you test for germ cell tumors?

In addition to a physical examination, the following tests may be used to diagnose a germ cell tumor:

  1. Biopsy. A biopsy is the removal of a small amount of tissue for examination under a microscope. …
  2. Blood tests. Alpha-fetoprotein (AFP). …
  3. Ultrasound. …
  4. Computed tomography (CT or CAT) scan. …
  5. Magnetic resonance imaging (MRI).

Are germ cell Tumours hereditary?

The cause of germ cell tumors isn’t fully known. Some gene defects passed on from parents to children (inherited) may increase the risk for germ cell tumors. Some genetic syndromes can cause abnormal growth of the male and female reproductive systems.

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Do germ cell tumors run in families?

[1] Ovarian germ cell tumors are rare malignancies. Familial clustering of testicular malignancies is well documented in literature. Children or siblings of affected family members are at higher risk for testicular germ cell tumors.

Is a germ cell tumor a solid tumor?

Germ cell tumors in the testes of an adolescent male commonly present as an enlarging, solid mass, which may be painful. Within the ovaries, germ cell tumors can usually be distinguished from ovarian cysts, which are much more common, using ultrasound. Germ cell tumors can spread to lymph nodes, lung, liver, and brain.

Are all germ cell tumors malignant?

Germ cell tumors may be cancerous (malignant) or noncancerous (benign). Although germ cells are usually in the reproductive organs, these cells can sometimes travel to other parts of the body and cause tumors, called extragonadal germ cell tumors.

How do they treat germ cell tumors?

Treatment options for germ cell tumors may include surgery to remove the tumor, chemotherapy with drugs that kill cancer cells and radiation therapy with powerful energy beams.

Can adults have germ cell tumors?

Extragonadal germ cell tumors are usually seen in children or young adults and typically arise in midline locations. In adults, the most common sites of primary extragonadal germ cell tumors are, in descending order, the mediastinum, retroperitoneum, and cranium.

What is germ cell tumor symptoms?

Common signs of germ cell tumors include: A mass on your ovaries or testicles. Belly pain and swelling (caused by tumor) Bathroom troubles (a hard time pooping or holding in your pee, if the tumor is near your pelvis)

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