What are the clinical features of Burkitt lymphoma?

Which of the following are often seen in patients with Burkitt’s lymphoma?

Major signs of Burkitt lymphoma include a soft-tissue mass associated with the involvement of the jaw or other facial bones, rapidly enlarged cervical lymph nodes, abdominal masses, and ascites.

How does Burkitt lymphoma present?

How does Burkitt’s lymphoma affect the body? Burkitt’s lymphoma presents with rapidly enlarging lymph node tumour masses involving the chest and/or the abdomen. It has a high tendency to spread to the central nervous system (brain and spinal cord), and can also involve the liver, spleen and bone marrow.

What are the stages of Burkitt’s lymphoma?

Stage I – Stage I disease means that the cancer is present at only one site in the body. Stage II – Stage II Burkitt’s lymphomas are present in more than one site, but both sites are on one side of the diaphragm. Stage III – Stage III disease is present in lymph nodes or other sites on both sides of the diaphragm.

What is Burkitt lymphoma?

Listen to pronunciation. (BER-kit lim-FOH-muh) An aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that occurs most often in children and young adults. The disease may affect the jaw, central nervous system, bowel, kidneys, ovaries, or other organs.

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What is the survival rate of Burkitt’s lymphoma?

Burkitt and Burkitt-like lymphoma

Treatment of limited stage (stage I and II) Burkitt lymphomas is usually very successful, with a long-term survival rate of over 90%. The long-term survival rate for children and teens with more advanced (stage III or IV) Burkitt lymphoma ranges from about 80% to 90%.

What is the difference between Hodgkin’s and Burkitt’s lymphoma?

Burkitt lymphoma is a form of non-Hodgkin’s lymphoma in which cancer starts in immune cells called B-cells. Recognized as a fast growing human tumor, Burkitt lymphoma is associated with impaired immunity and is rapidly fatal if left untreated.

Where is Burkitt’s lymphoma most common?

Burkitt lymphoma

  • Endemic (African) – the most common form, found mainly in central Africa, where it is associated with the Epstein Barr virus (EBV). …
  • Sporadic – a rarer form, seen in all parts of the world, that often develops in the abdomen with bone marrow involvement.

How can Burkitt lymphoma be prevented?

Prevention. There is no known prevention for Burkitt’s lymphoma. Using protection (condoms) during sex and avoiding intravenous drug use can effectively prevent HIV infection, which is associated with immunodeficiency-related Burkitt’s lymphoma.

Is there a cure for Burkitt’s lymphoma?

Burkitt lymphoma is curable with dose-intensive chemotherapy The dose-intensive chemotherapy that’s been developed to cure Burkitt lymphoma in pediatric patients is much better tolerated by children than adults, who can have severe side effects, especially if they are older or have other serious health conditions, such …

Can Burkitt’s lymphoma come back?

As Burkitt lymphoma is fast growing (high grade) you have treatment soon after diagnosis. If there is no sign of lymphoma following treatment, this is called remission. Sometimes, lymphoma can come back (relapse). You would usually then have more treatment.

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Is Burkitt’s lymphoma contagious?

EBV is contagious and most commonly spreads through bodily fluids, especially saliva. According to the Leukaemia Foundation, endemic Burkitt’s lymphoma is associated with EBV in nearly every case.